SOCIETY FOR HEALTH ALLIED RESEARCH & EDUCATION INDIA (SHARE INDIA)

TB Vaccine Study

TB Vaccine Study

Indian Council of Medical Research (ICMR), the Apex governing body in India for the formulation, coordination and promotion of biomedical research, selected SHARE INDIA-MediCiti Institute of Medical Sciences (MIMS) as a sub-site of Bhagwan Mahavir Medical Research Centre (BMMRC) for a vaccine study entitled ”A Phase-III, randomized, double-blind, three arm placebo controlled trial to evaluate the efficacy and safety of two vaccines VPM1002 and lmmuvac (Mw) in preventing Tuberculosis (TB) in healthy household contacts of newly diagnosed sputum positive pulmonary TB patients” (July 2020-June 2023).

The primary objective of the trial is to:

Evaluate the efficacy of VPM1002 and Immuvac by comparing the reduction in incidence of TB over 3-year period among Indian healthy household contacts of newly diagnosed sputum positive PTB patients vaccinated with VPM1002 and Immuvac in comparison to placebo.

The SHARE INDIA site was initiated on 13th July 2020 and has successfully enrolled 219 participants who are being followed-up as per the protocol timelines.